![]() Publication Date: Research Org.: Oak Ridge Associated Universities, TN (United States) Sponsoring Org.: USDOE Office of Energy Research, Washington, DC (United States) OSTI Identifier: 684486 Report Number(s): ORISE-99-0164-Vol.1 CONF-960536-PROC.-Vol.1 ON: DE99002903 TRN: IM9943%%177 DOE Contract Number: W-31109-ENG-38 Resource Type: Conference Resource Relation: Conference: 6. Argonne National Lab., IL (United States).of Illinois, Chicago, IL (United States). DePaul Univ., Chicago, IL (United States).Sources of uncertainty, and the use of these data in new epidemiological studies are discussed. In addition, a microdosimetric analysis is performed which considers the statistical variation of energy deposited more ยป within individual oocyte nuclei. ![]() Dose is estimated on a macroscopic scale by calculating the average dose deposited within the entire ovary. Data obtained in earlier dosimetric studies on the quantity of Ra-226 and/or Ra-228 ingested were used in this study. The dose to the ovaries can be attributed to four major sources: (1) external gamma irradiation from the containers of radium paint (2) alpha and (3) beta particle emissions due to sources which decay within the ovaries and (4) internal gamma irradiation released throughout the body. ![]() The goal of this work is to review and update the determination of dose to the ovaries from both external and internal radiation hazards in an attempt to correlate ovarian dose with these additional possible effects. Recently, there is a renewed interest on the part of epidemiologists studying additional possible effects (e.g., low birthrate and sex ratio). Earlier dosimetric studies (1950-1990) attempted to correlate the magnitude of biological effects (e.g., increased cancer incidence) with variations in radium uptake. In the 1920s, painters in the radium watch dial industry frequently tipped their brushes with their tongues resulting in the ingestion of radium-226 and/or radium-228.
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